Cancer Gene Therapy
Researchers from Central South University, Cancer Research Institute publish findings in cancer gene therapy
Published in Gene Therapy Weekly, August 6th, 2009
Scientists discuss in 'Inhibition of cell proliferation, migration and invasion by DNAzyme targeting MMP-9 in A549 cells' new findings in cancer gene therapy. According to recent research from Hunan, People's Republic of China, "Matrix metalloproteinases (MMPs) have been regarded as major critical molecules assisting tumor cells during angiogenesis and metastasis. Enhanced expression of matrix metalloproteinase-9 (MMP-9) is associated with human non-small cell lung cancer (NSCLC) invasion and metastasis."
"DNAzyme is a single-stranded DNA catalyst that can be engineered to bind to its complementary sequence in the target gene and cleave the mRNA. In this study, DNAzyme...
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Source: Gene Therapy Weekly (2009-08-06)
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