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Cystic Fibrosis

New findings from University of North Carolina in the area of cystic fibrosis described

Published in Gene Therapy Weekly, August 6th, 2009

"Grubb BR, Rogers TD, Boucher RC, Ostrowski LE. Ion transport across CF and normal murine olfactory and ciliated epithelium," scientists in the United States report.

"Am J Physiol Cell Physiol 296: C1301-C1309, 2009. First published March 25, 2009; doi:10.1152/ajpcell.00578.2008. -The nasal epithelium of the cystic fibrosis (CF) mouse has been used extensively in CF research because it exhibits ion transport defects similar to those of human CF airways. This tissue is composed of similar to 50% olfactory (OE) and similar to 50% ciliated epithelium (CE), and on the basis of previous observations, we hypothesized that a significant fraction of the bioelectric signals from...

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