Published in Gene Therapy Weekly, August 27th, 2009
"WWOX turned Out to Possess tumour Suppressor features despite the fact that the most basic (classical) way Of tumour suppressor gene inactivation involves both alleles (e.g. through deletions, point Mutations and promoter methylation), which Is very rare event in a case of WWOX, Occurring only in few cell lines. A large number of papers corroborate the phenomenon of correlation between the loss of WWOX...
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