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Cancer Gene Therapy

Reports from Winship Cancer Institute describe recent advances in cancer gene therapy

Published in Gene Therapy Weekly, August 27th, 2009

Investigators publish new data in the report 'LKB1 is required for adiponectin-mediated modulation of AMPK-S6K axis and inhibition of migration and invasion of breast cancer cells.' "Adiponectin is widely known as an adipocytokine with therapeutic potential for its markedly protective function in the pathogenesis of obesity-related disorders, metabolic syndrome, systemic insulin resistance, cardiovascular disease and more recently carcinogenesis. In the present study, we show that adiponectin inhibits adhesion, invasion and migration of breast cancer cells," investigators in the United States report.

"Further analysis of the underlying molecular mechanisms revealed that...

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