Stem Cell Research

CRi Oosight Imaging System a Key to Breakthrough Gene Replacement Method With Potential to Prevent Inherited Mitochondrial Diseases

Published in Gene Therapy Weekly, September 10th, 2009

U.S. researchers using CRi's Oosight™ imaging system have developed a gene transfer technique that has potential to prevent inherited diseases passed on from mothers to their children through mutated DNA in cell mitochondria. The research, which demonstrated the technique in rhesus monkeys, appears in the Aug. 26 issue of the journal Nature.

The group, headed by Dr. Shoukhrat Mitalipov of the Oregon National Primate Research Center and the Oregon Stem Cell Center, extracted the nuclear DNA from the mother's egg, guided by the Oosight system, and transplanted it into another egg that had the nucleus removed. The technique allowed the mother to pass along her...

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Source: Gene Therapy Weekly (2009-09-10)

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