Gene Therapy

New findings from W. Aung and co-researchers in the area of gene therapy described

Published in Gene Therapy Weekly, September 17th, 2009

According to a study from Chiba, Japan, "In vivo electroporation (EP) is an efficient method for effective gene transfer and is highly expected for application in anticancer gene therapy. Non-invasive monitoring of gene transfer/expression is critical for optimal gene therapy."

"Here we report in vivo optical and high-field magnetic resonance imaging (MRI) of EP-mediated transgene expression in a tumor model. Initially, we observed spatio-temporal change in in vivo EP-mediated transgene expression by optical imaging using red fluorescence protein (RFP) as a reporter gene. Next, we constructed a dual-reporter plasmid carrying a gene-encoding MRI reporter ferritin heavy...

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Source: Gene Therapy Weekly (2009-09-17)

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