Pancreatic Cancer Genetics
Scientists at Fudan University describe research in pancreatic cancer genetics
Published in Gene Therapy Weekly, September 17th, 2009
Research findings, 'Dual role of Ski in pancreatic cancer cells: tumor-promoting versus metastasis-suppressive function,' are discussed in a new report. "Ski used to be defined as an oncogene that contributes to the resistance of tumor cells to transforming growth factor-beta (TGF-beta)-induced growth arrest. As TGF-beta has a dual effect on tumor growth with both tumor-suppressing and -promoting activity depending on the stage of carcinogenesis and the cell type, the precise role of Ski in carcinogenesis remains unclear," investigators in Shanghai, People's Republic of China report.
"In this study, we show that downregulation of Ski through lentivirus-mediated RNA...
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Source: Gene Therapy Weekly (2009-09-17)
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