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IDT secures funding for new gene silencing research

Published in Gene Therapy Weekly, September 24th, 2009

Integrated DNA Technologies (IDT), the world leader in oligonucleotide synthesis, has been awarded $99,750 from the National Institutes of Health ARRA (American Recovery and Reinvestment Act) funding to continue work on its research project 'Gene Silencing with U1 Adapter Oligonucleotides.' As a new class of synthetic nucleic acids, the U1 adapters are capable of down-regulating the expression of genes of interest at the pre-mRNA stage, via a mechanism of action distinct from antisense or siRNA. This innovative new technology is based on oligos annealing to a specific region within the 3'-terminal exon of a gene to inhibit pre-mRNA processing and subsequent gene expression and can...

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