Lung Cancer
Researchers' work from Ohio State University focuses on lung cancer
Published in Gene Therapy Weekly, September 24th, 2009
"Fifteen percent of lung cancer cases occur in never-smokers and show characteristics that are molecularly and clinically distinct from those in smokers. Epidermal growth factor receptor (EGFR) gene mutations, which are correlated with sensitivity to EGFR-tyrosine kinase inhibitors (EGFR-TKIs), are more frequent in never-smoker lung cancers," scientists writing in the journal Proceedings of the National Academy of Sciences of the United States of America report.
"In this study, microRNA (miRNA) expression profiling of 28 cases of never-smoker lung cancer identified aberrantly expressed miRNAs, which were much fewer than in lung cancers of smokers and included...
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Source: Gene Therapy Weekly (2009-09-24)
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