Breast Cancer
Data from V.M. Golubovskaya and colleagues advance knowledge in breast cancer
Published in Gene Therapy Weekly, October 15th, 2009
"To study the direct effect of FAK on breast tumorigenesis, we developed Tet-ON (tetracycline-inducible) system of MCF-7 breast cancer cells stably transfected with FAK or dominant-negative, C-terminal domain of FAK (FAK-CD), and also FAKsiRNA with silenced FAK MCF-7 stable cell line. Increased expression of FAK in isogenic Tet-inducible MCF-7 cells caused increased cell growth, adhesion and soft agar...
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Source: Gene Therapy Weekly (2009-10-15)
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