Escherichia coli
New research on Escherichia coli from University of Birmingham summarized
Published in Gene Therapy Weekly, October 15th, 2009
"Previously we made several NfsB mutants that show better activity with CB1954 in a cell-killing assay in E. coli. Here we compare the kinetic parameters of wild-type NfsB with CB1954 to those of the most active single, double, and triple mutants isolated to date. For wild-type NAB the global kinetic parameters for both k(cat) and K-m for CB1954 are about 20-fold higher than previously...
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Source: Gene Therapy Weekly (2009-10-15)
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