Cancer Gene Therapy
Reports outline cancer gene therapy research from University of Kuopio
Published in Gene Therapy Weekly, October 22nd, 2009
According to recent research published in the journal Human Gene Therapy, "One of the main objectives of cancer therapy is to enhance the effectiveness of the drug by concentrating it at the target site and to minimize the undesired side effects to nontarget cells. We have previously constructed a fusion protein, Lodavin, consisting of avidin and the endocytotic part of the low-density lipoprotein receptor, and demonstrated its applicability to transient drug targeting in vivo."
"In this study we produced a lentiviral vector expressing this fusion protein and evaluated its safety and efficacy. The results showed that lentivirus-mediated gene transfer led to...
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Source: Gene Therapy Weekly (2009-10-22)
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