Life Sciences
New life sciences research reported from Pennsylvania State University
Published in Gene Therapy Weekly, October 29th, 2009
According to recent research published in the Journal of Nutrition, "Despite having a similar structure, various conjugated linoleic acid (CLA) isomers have a distinct gene expression pattern in RAW 264.7 (RAW) cells, a mouse macrophage cell line. Among the 5 CLA isomers tested [9cis(Z),11 trans(E)-, 9Z,11Z-, 9E,11E-, 10E,12Z-, and 11Z,13E-CLA], only 9E,11E-CLA induced the endogenous antiinflammatory molecule, interleukin (IL)-1 receptor antagonist (IL-1 Ra), in RAW cells."
"In this study, the mechanism and effects of IL-1 Ra regulation by 9E,11E-CLA in RAW cells was studied in detail. 9E,11E-CLA induced IL-1 Ra in a dose- and time-dependent manner, whereas it...
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Source: Gene Therapy Weekly (2009-10-29)
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