Gene Therapy

Data from United Arab Emirates University provide new insights into gene therapy

Published in Gene Therapy Weekly, October 29th, 2009

"The mouse mammary tumor virus (MMTV) is unique from other retroviruses in having multiple viral promoters, which can be regulated by hormones in a tissue specific manner. This unique property has lead to increased interest in studying MMTV replication with the hope of developing MMTV based vectors for human gene therapy," investigators in Al Ain, United Arab Emirates report.

"However, it has recently been reported that related as well as unrelated retroviruses can cross-package each other's genome raising safety concerns towards the use of candidate retroviral vectors for human gene therapy. Therefore, using a trans complementation assay, we looked at the ability of...

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Source: Gene Therapy Weekly (2009-10-29)

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