Published in Gene Therapy Weekly, November 5th, 2009
"Induced p53 beta and diminished Delta 133p53 were associated with replicative senescence, but not oncogene-induced senescence, in normal human fibroblasts. The replicatively senescent fibroblasts also expressed increased levels of miR-34a, a p53-induced microRNA(5-9), the antisense inhibition of which delayed the...
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