Gene Therapy Weekly
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Breast Cancer
Research on breast cancer described by scientists at University of Tokyo
November 12th, 2009
"We here report identification and characterization of Required for Cell Differentiation I homolog (RQCD1) as a potential therapeutic target for breast cancer. Gene-expression profiling analysis of breast cancer cells, semi-quantitative RT-PCR, Northern blotting and Western blotting confirmed RQCD1 to be frequently up-regulated in breast cancer specimens and breast cancer cell lines," scientists in Tokyo, Japan report. "On the other hand, its expression was very weak or hardly detectable in normal human tissues except testis, indicating this molecule to be a novel cancer-testis antigen. Treatment of breast cancer cell lines with siRNA targeting RQCD1 drastically...
Source: Gene Therapy Weekly (2009-11-12)
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