DNA Research
Studies from University of Memphis in the area of DNA research published
Published in Gene Therapy Weekly, December 3rd, 2009
"Complexes formed from DNA and polycations are of interest because of their potential use in gene therapy; however, there remains a lack of understanding of the structure and formation of DNA-polycation complexes at atomic scale. In this work, molecular dynamics simulations of the DNA duplex d(CGCGAATTCGCG) in the presence of polycation chains are carried out to shed light on the specific atomic interaction that result in complex formation," scientists in the United States report.
"The structures of complexes formed from DNA with polyethylenimine, which is considered one of the most promising DNA vector candidates, and a second polycation, poly-L-lysine, are compared....
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Source: Gene Therapy Weekly (2009-12-03)
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