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Research from Oregon State University reveals new findings on gene therapy

Published in Gene Therapy Weekly, February 4th, 2010

A report, 'Identification of MIR390a precursor processing-defective mutants in Arabidopsis by direct genome sequencing,' is newly published data in Proceedings of the National Academy of Sciences of the United States of America. According to recent research from the United States, "Transacting siRNA (tasiRNA) biogenesis in Arabidopsis is initiated by microRNA (miRNA) -guided cleavage of primary transcripts. In the case of TAS3 tasiRNA formation, ARGONAUTE7 (AGO7)-miR390 complexes interact with primary transcripts at two sites, resulting in recruitment of RNA-DEPENDENT RNA POLYMERASE6 for dsRNA biosynthesis."

"An extensive screen for Arabidopsis mutants with...

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