Gene Therapy
New findings from National Tsing Hua University in the area of gene therapy published
Published in Gene Therapy Weekly, February 4th, 2010
"Baculovirus has emerged as a novel gene delivery and vaccine vector, and the demand for purified baculovirus is rising due to the increasing in vivo applications. Since the baculoviral envelope protein gp64 is a glycoprotein, we aimed to develop a concanavalin A (Con A) chromatography process, which harnessed the possible affinity interaction between gp64 and Con A, for simple and effective baculovirus purification, Throughout the purification process the virus stability and recovery were assessed by quantifying the virus transducing titers [TT, defined as transducing units (TU) per milliliter] and viral particles (VP)," scientists in Hsinchu, Taiwan report.
"We found...
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Source: Gene Therapy Weekly (2010-02-04)
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