Inflammation Immunology
Studies from Shimane University School of Medicine, Department of Internal Medicine II have provided new information about inflammation immunology
Published in Gene Therapy Weekly, February 4th, 2010
Current study results from the report, 'A20 is an early responding negative regulator of Toll-like receptor 5 signalling in intestinal epithelial cells during inflammation,' have been published. According to recent research from Izumo, Japan, "Several negative regulatory mechanisms control Toll-like receptor (TLR)-mediated inflammatory responses and restore immune system balance, including the zinc-finger protein A20, a negative regulator of TLR signalling that inhibits nuclear factor kappa B (NF-kappaB) activity. In the present study, we investigated TLR-5-mediated A20 expression and its role in intestinal epithelial cells (IECs) during inflammation."
"HCT-15 and HT-29...
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Source: Gene Therapy Weekly (2010-02-04)
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