Squamous Cell Carcinoma Therapy
New squamous cell carcinoma therapy study results from Johns Hopkins University, Department of Dermatology described
Published in Gene Therapy Weekly, February 11th, 2010
Researchers detail in 'Phospho-DeltaNp63alpha/NF-Y protein complex transcriptionally regulates DDIT3 expression in squamous cell carcinoma cells upon cisplatin exposure,' new data in squamous cell carcinoma. "Cisplatin remains the most important chemotherapeutic agent for patients with human head and neck cancer. However, tumor cells often develop resistance to cisplatin-induced apoptosis," investigators in the United States report.
"We previously found that head and neck squamous cell carcinoma (HNSCC) cells exposed to cisplatin display a marked ATM-induced phosphorylation of DeltaNp63alpha. However, the mutated Np63-S385G failed to undergo phosphorylation by ATM...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Gene Therapy Weekly
Source: Gene Therapy Weekly (2010-02-11)
More Articles from Gene Therapy Weekly
- Angiogenesis
Studies from University of Birmingham yield new data on angiogenesis - Anxiety Disorders
Data from A. Bahi et al provide new insights into anxiety disorders - Aspergillus Fumigatus
Recent studies from University of Alcala add new data to aspergillus fumigatus - Asthma
Data from Chang Gung University advance knowledge in asthma - Bird Flu
Study findings from Pohang University of Science & Technology provide new insights into bird flu - Bone Morphogenetic Protein
Findings in bone morphogenetic protein reported from University of Munich - More from this issue of Gene Therapy Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
