Aspergillus Fumigatus

Recent studies from University of Alcala add new data to aspergillus fumigatus

Published in Gene Therapy Weekly, February 11th, 2010

"The identification of essential genes represents a critical step in the discovery of novel therapeutic targets in Aspergillus fumigatus. Structural analyses of the Saccharomyces cerevisiae RNA triphosphatase pointed out this enzyme as an attractive therapeutic target for fungal infections," researchers in Madrid, Spain report.

"In addition, demonstration of the essentiality of the S. cerevisiae RNA triphosphatase encoding gene enhanced the value of this potential therapeutic target. Nevertheless, consideration of a fungal RNA triphosphatase as an ideal therapeutic target needs confirmation of the essentiality of the respective gene in a fungal pathogen. In this work,...

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Source: Gene Therapy Weekly (2010-02-11)

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