Neurogenetic
New neurogenetic research reported from University of Utah, Huntsman Cancer Institute
Published in Gene Therapy Weekly, February 18th, 2010
Data detailed in 'Dnmt3 and G9a cooperate for tissue-specific development in zebrafish' have been presented. According to recent research from the United States, "Although DNA methylation is critical for proper embryonic and tissue-specific development, how different DNA methyltransferases affect tissue-specific development and their targets remains unknown. We address this issue in zebrafish through antisense-based morpholino knockdown of Dnmt3 and Dnmt1."
"Our data reveal that Dnmt3 is required for proper neurogenesis, and its absence results in profound defects in brain and retina. Interestingly, other organs such as intestine remain unaffected suggesting...
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Source: Gene Therapy Weekly (2010-02-18)
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