Glioblastoma

Research from N.G. Thaker et al broadens understanding of glioblastoma

Published in Gene Therapy Weekly, February 18th, 2010

According to a study from the United States, "Glioblastoma multiforme (GBM) is a high-grade brain malignancy arising from astrocytes. Despite aggressive surgical approaches, optimized radiation therapy regimens, and the application of cytotoxic chemotherapies, the median survival of patients with GBM from time of diagnosis remains less than 15 months, having changed little in decades."

"Approaches that target genes and biological pathways responsible for tumorigenesis or potentiate the activity of current therapeutic modalities could improve treatment efficacy. In this regard, several genomic and proteomic strategies promise to impact significantly on the drug discovery...

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Source: Gene Therapy Weekly (2010-02-18)

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