Colon Cancer

Research from C.X. Liu and co-authors in the area of colon cancer published

Published in Gene Therapy Weekly, February 25th, 2010

According to a study from the United States, "Targeting of a specific subset of cells is mandatory for the successful application of siRNA mediated silencing in anticancer therapy. A recent theory suggests that colon cancer is sustained by a small subpopulation of cells, termed cancer stem cells (CSCs)."

"These cells are characterized by their innate drug resistance properties, which is one of the key factors of chemotherapy failure. The goal of this study was to assess whether a novel siRNA delivery carrier, with an appropriate siRNA, targeted to CD133+ cells has the potential to improve the efficacy of conventional chemotherapy. In this study, a novel synthetic siRNA...

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Source: Gene Therapy Weekly (2010-02-25)

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