Endometriosis

Investigators at University of Bari have published new data on endometriosis

Published in Gene Therapy Weekly, March 4th, 2010

According to a study from Bari, Italy, "The aim of this study was to evaluate the factors predisposing to implants of endometriotic lesions in normal ovarian cortexes of women with and without endometriosis by assessing the expression of pro-apoptotic and anti-apoptotic factors and follicular density. Ovarian biopsies were performed during laparoscopy in 18 patients with endometrioma and in 10 healthy women."

"Detection of apoptosis was performed with terminal deoxynucleotidyl transferase-mediated dUTP nick-end labelling assay. p53 and BCL2 proteins were assessed by immunohistochemistry. Quantitative real-time polymerase chain reaction was performed to evaluate BAX,...

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Source: Gene Therapy Weekly (2010-03-04)

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