Life Sciences
Data on life sciences discussed by researchers at Mayo Clinic, Department of Molecular Medicine
Published in Gene Therapy Weekly, March 11th, 2010
New investigation results, 'Single-cycle viral gene expression, rather than progressive replication and oncolysis, is required for VSV therapy of B16 melanoma,' are detailed in a study published in Gene Therapy. According to a study from the United States, "A fully intact immune system would be expected to hinder the efficacy of oncolytic virotherapy by inhibiting viral replication. Simultaneously, however, it may also enhance antitumor therapy through initiation of proinflammatory, antiviral cytokine responses at the tumor site."
"The aim of this study was to investigate the role of a fully intact immune system on the antitumor efficacy of an oncolytic virus. In...
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Source: Gene Therapy Weekly (2010-03-11)
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