Antisense Technology
Research from National Institutes of Health has provided new information about antisense technology
Published in Gene Therapy Weekly, March 11th, 2010
New investigation results, 'Estrogen down-regulation of the Scx gene is mediated by the opposing strand-overlapping gene Bop1,' are detailed in a study published in Journal of Biological Chemistry. "Recent genome-wide transcriptome studies suggest the presence of numerous bidirectional overlapping coding gene pairs in mammalian genomes. Various antisense RNAs are reported as non-coding RNAs that regulate the expression of sense RNA," investigators in the United States report.
"However, it is still unclear whether the expression of bidirectional overlapping coding genes are regulated by the opposite strand gene transcript acting as a non-coding RNA. Bop1 and Scx...
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Source: Gene Therapy Weekly (2010-03-11)
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