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Bacillus Subtilis

Research from Tokai University in Bacillus subtilis provides new insights

Published in Gene Therapy Weekly, March 18th, 2010

New investigation results, 'Functional analysis of the stability determinant AlfB of pBET131, a miniplasmid derivative of bacillus subtilis (natto) plasmid pLS32,' are detailed in a study published in Journal of Bacteriology. According to a study from Shizuoka, Japan, "Bacillus subtilis plasmid pBET131 is a derivative of pLS32, which was isolated from a natto strain of Bacillus subtilis. The DNA region in pBET131 that confers segregational stability contains an operon consisting of three genes, of which alfA, encoding an actin-like ATPase, and alfB are essential for plasmid stability."

"In this work, the alfB gene product and its target DNA region were studied in...

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