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Gene Therapy

New gene therapy data have been reported by M.K. Jang and co-authors

Published in Gene Therapy Weekly, April 1st, 2010

New research, 'The tyrosine phosphatase, SHP-1, is involved in bronchial mucin production during oxidative stress,' is the subject of a report. According to recent research from Seoul, Korea, "Mucus hypersecretion is a clinically important manifestation of chronic inflammatory airway diseases, such as asthma and Chronic obstructive pulmonary disease (COPD). Mucin production in airway epithelia is increased under conditions of oxidative stress."

"Src homology 2 domain-containing protein tyrosine phosphatase (SHP)-1 suppression is related to the development of airway inflammation and increased ROS levels. In this study, we investigated the role of SHP-1 in mucin secretion...

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