Life Sciences
Researchers from University of Sydney publish findings in life sciences
Published in Gene Therapy Weekly, April 8th, 2010
Research findings, 'Activated protein C utilizes the angiopoietin/Tie2 axis to promote endothelial barrier function,' are discussed in a new report. According to recent research from Australia, "Activated protein C (APC) is an anticoagulant, approved as a treatment for severe sepsis, that can prevent apoptosis, inflammation, and vascular leakage. The aim of this study was to investigate whether APC protects endothelial barrier function through the angiopoietin (Ang)/Tie2 axis."
"APC significantly up-regulated gene and protein expression of Tie2 and Ang1 in a dose (0.01-10 microg/ml)-and time (0.5-24 h)-dependent manner in human umbilical vein endothelial cells (HUVECs)....
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Source: Gene Therapy Weekly (2010-04-08)
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