Gene Therapy

Studies conducted at University of Western Ontario, Department of Surgery on gene therapy recently published

Published in Gene Therapy Weekly, April 15th, 2010

A report, 'siRNA specific delivery system for targeting dendritic cells,' is newly published data in Methods In Molecular Biology. "siRNA therapy offers immense potential for clinical application. Under physiological conditions, however, siRNA was demonstrated to have a short half-life," scientists writing in the journal Methods In Molecular Biology report.

"Additionally, it may also cause ubiquitous gene silencing as it does not possess a tissue-specific homing mechanism. Thus, the rate-limiting step in the emergence of siRNA as a potential therapeutic agent is the current lack of a safe and tissue-or cell-specific in vivo delivery system. Herein, we...

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Source: Gene Therapy Weekly (2010-04-15)

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