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Chondrosarcoma Cell Biology

New chondrosarcoma cell biology study findings recently were reported by researchers at China Medical University, Graduate Institute of Pharmaceutical Chemistry

Published in Gene Therapy Weekly, April 22nd, 2010

Fresh data on chondrosarcoma are presented in the report 'Cyclooxygenase-2 enhances alpha2beta1 integrin expression and cell migration via EP1 dependent signaling pathway in human chondrosarcoma cells.' According to recent research published in the journal Molecular Cancer, "Cyclooxygenase (COX)-2, the inducible isoform of prostaglandin (PG) synthase, has been implicated in tumor metastasis. Interaction of COX-2 with its specific EP receptors on the surface of cancer cells has been reported to induce cancer invasion."

"However, the effects of COX-2 on migration activity in human chondrosarcoma cells are mostly unknown. In this study, we examined whether COX-2 and...

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