Gene Therapy
Study data from Yeungnam University, College of Pharmacy provide new insights into gene therapy
Published in Gene Therapy Weekly, April 22nd, 2010
Research findings, 'The NRF2-heme oxygenase-1 system modulates cyclosporin A-induced epithelial-mesenchymal transition and renal fibrosis,' are discussed in a new report. According to a study from South Korea, "Epithelial-mesenchymal transition (EMT) is an underlying mechanism of tissue fibrosis, generating myofibroblasts, which serve as the primary source of extracellular matrix production from tissue epithelial cells. Recently, EMT has been implicated in immunosuppressive cyclosporin A (CsA)-induced renal fibrosis."
"In this study, the potential role of NRF2, which is the master regulator of genes associated with the cellular antioxidant defense system, in CsA-induced...
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Source: Gene Therapy Weekly (2010-04-22)
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