Gene Therapy
New gene therapy study findings reported from New York Medical College, Department of Physiology
Published in Gene Therapy Weekly, April 29th, 2010
New research, 'Roles of CYP2C29 and RXR gamma in vascular EET synthesis of female mice,' is the subject of a report. According to recent research published in the American Journal of Physiology Regulatory, Integrative and Comparative Physiology, "We aimed to identify which cytochrome P-450 (CYP) family/subfamily, as well as related transcription factor(s), is responsible for the estrogen-dependent synthesis of epoxyeicosatrienoic acids (EETs) to initiate shear stress-induced vasodilation. Microarray analysis indicated a significant upregulation of CYP2C29 and retinoid X receptor gamma (RXRgamma) in isolated mesenteric arteries/arterioles of female endothelial nitric oxide...
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Source: Gene Therapy Weekly (2010-04-29)
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