Experimental Lung Transplantation
Findings from University of Cambridge broaden understanding of experimental lung transplantation
Published in Gene Therapy Weekly, May 13th, 2010
"The beta 2.7 RNA transcript encoded by human cytomegalovirus (CMV) has been shown to stabilize Complex I by direct physical interaction. In this study, we investigated whether stabilizing Complex I in EC in an in vitro model of ischemia could prevent apoptosis. Lentiviral vectors expressing a full-length beta 2.7 RNA were generated from a human immunodeficiency virus-1 (HIV-1) construct, in which the viral promoter had been inactivated and...
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Source: Gene Therapy Weekly (2010-05-13)
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