Gene Therapy
Recent findings from Ordway Research Institute highlight research in gene therapy
Published in Gene Therapy Weekly, May 13th, 2010
Researchers detail in 'Function-based gene identification using enzymatically generated normalized shRNA library and massive parallel sequencing,' new data in gene therapy. "As a general strategy for function-based gene identification, an shRNA library containing approximately 150 shRNAs per gene was enzymatically generated from normalized (reduced-redundance) human cDNA. The library was constructed in an inducible lentiviral vector, enabling propagation of growth-inhibiting shRNAs and controlled activity measurements," researchers in the United States report.
"RNAi activities were measured for 101 shRNA clones representing 100 human genes and for 201 shRNAs derived...
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Source: Gene Therapy Weekly (2010-05-13)
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