Heart Failure
Research from Mount Sinai School of Medicine broadens understanding of heart failure
Published in Gene Therapy Weekly, May 20th, 2010
Current study results from the report, 'Sarcoplasmic reticulum Ca(2+) ATPase as a therapeutic target for heart failure,' have been published. "The cardiac isoform of the sarco/endoplasmic reticulum Ca(2+)ATPase (SERCA2a) plays a major role in controlling excitation/contraction coupling. In both experimental and clinical heart failure, SERCA2a expression is significantly reduced which leads to abnormal Ca(2+) handling and deficient contractility," researchers in the United States report.
"A large number of studies in isolated cardiac myocytes and in small and large animal models of heart failure showed that restoring SERCA2a expression by gene transfer corrects the...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Gene Therapy Weekly
Source: Gene Therapy Weekly (2010-05-20)
More Articles from Gene Therapy Weekly
- Hemic and Immune Systems
Data on hemic and immune systems detailed by researchers at University Medical Center - Stem Cell Research
Data on stem cell research detailed by M. Sioud and co-authors - Enzymes and Coenzymes
Findings from W. Zalewski et al in enzymes and coenzymes reported - Nanoparticles
Findings from Zhejiang University broaden understanding of nanoparticles - Carboxylic Acids
New findings from Yale University in the area of carboxylic acids published - Eicosanoids
New findings in eicosanoids described from University of Munich - More from this issue of Gene Therapy Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
