Cell Biology

Research findings from University Medical Center, Department of Immunology update understanding of cell biology

Published in Gene Therapy Weekly, May 27th, 2010

Current study results from the report, 'Langerhans cells: critical regulators of skin immunity,' have been published. "Langerhans cells (LC) are members of the heterogenous family of professional antigen presenting dendritic cells (DC). They are identified by the C-type lectin receptor Langerin and form a contiguous network in the epidermis," investigators in Rotterdam, Netherlands report.

"Consequently, LC are an integral part of the skin barrier to the environment and were considered to be critical inducers of skin immunity, whereas dermal DC were largely overlooked. However, with the identification of a distinct subset of Langerin expressing dermal DC, the situation...

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Source: Gene Therapy Weekly (2010-05-27)

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