Gene Therapy
Research from Institute for Clinical Transfusion Medicine and Immunogenetics Ulm has provided new information about gene therapy
Published in Gene Therapy Weekly, June 3rd, 2010
Data detailed in 'Zinc-finger nuclease-induced gene repair with oligodeoxynucleotides: wanted and unwanted target locus modifications' have been presented. "Correcting a mutated gene directly at its endogenous locus represents an alternative to gene therapy protocols based on viral vectors with their risk of insertional mutagenesis. When solely a single-stranded oligodeoxynucleotide (ssODN) is used as a repair matrix, the efficiency of the targeted gene correction is low," investigators in Ulm, Germany report.
"However, as shown with the homing endonuclease I-SceI, ssODN-mediated gene correction can be enhanced by concomitantly inducing a DNA double-strand break (DSB)...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Gene Therapy Weekly
Source: Gene Therapy Weekly (2010-06-03)
More Articles from Gene Therapy Weekly
- Ovarian Cancer
Data on ovarian cancer published by researchers at University of Washington - Proinsulin
Data on proinsulin published by researchers at University of Alabama - Solid Cancer
Investigators at University of Tokyo have published new data on solid cancer - Lipids
MicroRNA and host gene play key role in regulating cholesterol pathways - Breast Cancer
New breast cancer study findings reported from University of Missouri - Biomolecular Screening
New findings from D.W. Beacham and co-authors describe advances in biomolecular screening - More from this issue of Gene Therapy Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
