Colon Cancer
Reports summarize colon cancer study results from Gifu International Institute of Biotechnology, Department of Medical Oncology
Published in Gene Therapy Weekly, June 10th, 2010
Investigators publish new data in the report 'Role of anti-oncomirs miR-143 and -145 in human colorectal tumors.' "We examined the expression levels of microRNAs (miRNAs (miRs)) in colorectal tumors (63 cancer specimens and 65 adenoma specimens) and paired non-tumorous tissues. Decreased expression of miR-143 and -145 was frequently observed in the adenomas and cancers tested, compared with miR-34a downregulation and miR-21 upregulation," researchers in Kakamigahara, Japan report.
"Expression profiles of miR-143 and -145 were not associated with any clinical features. As the downregulation of miR-143 and -145 was observed even in the early phase of adenoma formation,...
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Source: Gene Therapy Weekly (2010-06-10)
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