Bone Research
New bone research study results reported from University of Melbourne, St. Vincent's Institute
Published in Gene Therapy Weekly, June 17th, 2010
A new study, 'Calcitonin impairs the anabolic effect of PTH in young rats and stimulates expression of sclerostin by osteocytes,' is now available. "The therapeutic goal of increasing bone mass by co-treatment of parathyroid hormone (PTH) and an osteoclast inhibitor has been complicated by the undefined contribution of osteoclasts to the anabolic activity of PTH. To determine whether active osteoclasts are required at the time of PTH administration, we administered a low dose of the transient osteoclast inhibitor salmon calcitonin (sCT) to young rats receiving an anabolic PTH regimen," researchers in Fitzroy, Australia report.
"Co-administration of sCT significantly...
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Source: Gene Therapy Weekly (2010-06-17)
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