Gene Therapy
New gene therapy research from University of Pennsylvania described
Published in Gene Therapy Weekly, June 24th, 2010
A new study, 'The benefit of hydrophobic domain asymmetry on the efficacy of transfection as measured by in vivo imaging,' is now available. According to a study from the United States, "We, and others, have observed that the structure of cationic lipids appears to have a significant effect on the transfection efficacy of optimized nucleic acid/cationic lipid complexes (lipoplexes) used for in vitro and in vivo gene delivery and expression. Although there are many in vitro comparisons of lipid reagents for gene delivery, few comparisons have been made in vivo."
"We previously reported the effects of changes in hydrophobic domain chain length and chain asymmetry, changes...
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Source: Gene Therapy Weekly (2010-06-24)
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