Luminescent Proteins
Studies from University of California, Department of Medicine further understanding of luminescent proteins
Published in Gene Therapy Weekly, July 1st, 2010
Investigators publish new data in the report 'Optimization of enzyme-substrate pairing for bioluminescence imaging of gene transfer using Renilla and Gaussia luciferases.' "Bioluminescence imaging (BLI) permits the non-invasive quantification and localization of transduction and expression by gene transfer vectors. The tendency of tissue to attenuate light in the optical region, however, limits the sensitivity of BLI," researchers in the United States report.
"Improvements in light output from bioluminescent reporter systems would allow the detection of lower levels of expression, smaller numbers of cells and expression from deeper and more attenuating tissues within an...
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Source: Gene Therapy Weekly (2010-07-01)
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