Biomacromolecules
New biomacromolecules research has been reported by scientists at Ecole Polytechnique de Montreal
Published in Gene Therapy Weekly, August 12th, 2010
A new study, 'One-step analysis of DNA/chitosan complexes by field-flow fractionation reveals particle size and free chitosan content,' is now available. "The composition of samples obtained upon complexation of DNA with chitosan was analyzed by asymmetrical flow field flow fractionation (AF4) with online UV-visible, multiangle light scattering (MALS), and dynamic light scattering (DLS) detectors. A chitosan labeled with rhodamine B to facilitate UV-vis detection of the polycation was complexed with DNA under conditions commonly used for transfection (chitosan glucosamine to DNA phosphate molar ratio of 5)," investigators in Montreal, Canada report.
"AF4 analysis...
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Source: Gene Therapy Weekly (2010-08-12)
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