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Stem Cell Research

Data on stem cell research discussed by researchers at Chinese Academy of Sciences

Published in Gene Therapy Weekly, August 19th, 2010

A report, 'Role of Lef1 in sustaining self-renewal in mouse embryonic stem cells,' is newly published data in Journal of Genetics and Genomics = Yi Chuan Xue Bao. According to a study from Guangzhou, People's Republic of China, "Embryonic stem cells (ESCs) can self-renew indefinitely while maintaining the ability to generate all three germ-layer derivatives. Despite the importance of ESCs in developmental biology and their potential impact on regenerative medicine, the molecular mechanisms controlling ESC behavior are incompletely understood."

"Previously, activation of the canonical Wnt signaling pathway has been shown to contribute to mouse ESC self-renewal....

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