Vaccinia

Data on vaccinia discussed by J.N. Brewoo and colleagues

Published in Gene Therapy Weekly, September 9th, 2010

Current study results from the report, 'Efficacy and safety of a modified vaccinia Ankara (MVA) vectored plague vaccine in mice,' have been published. "The efficacy and safety of plague vaccines based on the modified vaccinia Ankara (MVA) viral vector was evaluated," researchers in the United States report.

"MVA recombinants were constructed expressing Yersinia pestis antigens under the translational control of the encephalomyocarditis virus (EMCV) internal ribosomal entry site (IRES) and/or fused to the tissue plasminogen activator (tPA) secretory signal. A MVA/Y. pestis recombinant that expressed a truncated version of the low-calcium response V antigen...

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Source: Gene Therapy Weekly (2010-09-09)

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