Diabetes
Investigators at University of Virginia, Department of Anesthesiology publish new data on diabetes
Published in Gene Therapy Weekly, September 23rd, 2010
New investigation results, 'In vivo silencing of the Ca(V)3.2 T-type calcium channels in sensory neurons alleviates hyperalgesia in rats with streptozocin-induced diabetic neuropathy,' are detailed in a study published in Pain. According to a study from the United States, "Earlier, we showed that streptozocin (STZ)-induced type 1 diabetes in rats leads to the development of painful peripheral diabetic neuropathy (PDN) manifested as thermal hyperalgesia and mechanical allodynia accompanied by significant enhancement of T-type calcium currents (T-currents) and cellular excitability in medium-sized dorsal root ganglion (DRG) neurons. Here, we studied the in vivo and in vitro effects of...
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Source: Gene Therapy Weekly (2010-09-23)
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