Glioblastomas
Data from Qilu Hospital of Shandong University, Department of Neurosurgery provide new insights into glioblastomas
Published in Gene Therapy Weekly, September 30th, 2010
Fresh data on glioblastomas are presented in the report 'Rho-kinase inhibitor, fasudil, suppresses glioblastoma cell line progression in vitro and in vivo.' "There is growing evidence that the Rho/Rho-kinase (ROCK) signaling pathway is upregulated in tumors and plays a key role in cancer invasion and proliferation. The aim of this study was to explore the anti-tumor effects of Rho/ROCK inhibitor, fasudil, including the possible mechanisms involved in the suppression of the glioblastoma (GBM) cell line progression in vitro and in vivo," investigators in People's Republic of China report.
"After T98G and U251 cells were treated with various concentrations of fasudil,...
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Source: Gene Therapy Weekly (2010-09-30)
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