Lipoproteins
Investigators at University of Crete, Institute of Molecular Biology and Biotechnology zero in on lipoproteins
Published in Gene Therapy Weekly, October 21st, 2010
Current study results from the report, 'Regulation of human apolipoprotein m gene expression by orphan and ligand-dependent nuclear receptors,' have been published. "Apolipoprotein M (apoM) plays an important role in the biogenesis and the metabolism of anti-atherogenic HDL particles in plasma and is expressed primarily in the liver and the kidney. We investigated the role of hormone nuclear receptors in apoM gene regulation in hepatic cells," scientists in Greece report.
"Overexpression via adenovirus-mediated gene transfer and siRNA-mediated gene silencing established that hepatocyte nuclear factor 4 (HNF-4) is an important regulator of apoM gene transcription in...
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Source: Gene Therapy Weekly (2010-10-21)
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